Increased aminotransferases in a 12-year-old girl.
نویسندگان
چکیده
Increased aminotransferases often indicate hepatic injury but are also increased with damage to heart and muscle (1 ). Testing for creatine kinase is helpful, especially when the ratio of aspartate aminotransferase to alanine aminotransferase is 3:1, a value uncommon with liver injury. In acute liver injury the aspartate aminotransferase/alanine aminotransferase ratio is usually 2:1. When measured, the patient’s creatine kinase was 32 000 (reference interval 72–367 U/L), confirming that increased aminotransferases were from acute muscle injury (rhabdomyolysis). She had participated in physical education activities (that were extreme sport–like and/or very highly strenuous) Department of Pathology and Laboratory, Cook Children’s Medical Center, Fort Worth, TX. * Address correspondence to this author at: Department of Pathology and Laboratory, 801 7th Ave., Fort Worth, TX 76104. E-mail van.leungpineda@ cookchildrens.org. Received October 15, 2013; accepted November 14, 2013. DOI: 10.1373/clinchem.2013.217760 Table 1. Initial chemistry results.
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 60 6 شماره
صفحات -
تاریخ انتشار 2014